One of the more common tumors to affect the brain is a meningioma, a benign tumor arising from the coverings of the brain. The pre-operative embolizatin of these lesions, especially when they are large, has been shown to reduce operative complications and lead to shorter hospital stays. The use of intracranial intra-arterial chemotherapy for primary malignant tumors of the brain has not been consistently effective.
Many vascular tumors of the neck and skull base respond very favorably to pre-operative embolization. This technique is gaining wide acceptance with the ENT surgeon.
Metastatic tumors often spread to the spine.
Operative therapy can be associated with excessive blood loss. These patients
may benefit from preopeartive embolization.
Compression fractures of the spine are an all too common occurrence among the elderly. Typically, related to osteoporosis, a loss of the minieral content of the bone, compression fractures are quite painful and lead to significant loss of mobility in those patients. The x-ray directed placement of bone cement into the collapsed verteral body usually results in the prompt relief of, or significant improvement in back pain. This allows a quicker return to normal activities and an improved quality of life.
Usually acquired in mid-life, often in conjunction with hypertension and atherosclerosis, aneurysms are defects in the walls of the arteries of the brain. Resembling small bubbles or blisters on the arterial wall, they become progressively larger over time. If the aneurysm ruptures, bleeding occurs into or around the brain often resulting in death or permanent neurologic disability (stroke).
These congential lesions, present at birth, represent a disorganized tangle of abnormal arteries and veins wihtin the substance of the brain. Associated with cerebral anuerysms, these vascular malformations can be a cause of seizures and hemorrhage within the brain
A leading cause of death and permanent disability among Americans, stroke occurs when an artery within the brain is blocked, usually by a blood clot coming from the heart or from arterial blockage of the arteries in the neck. The part of the brain supplied by the blocked artery rapidly becomes ischemic (suffers from an inadequate supply of oxygen) and brain injury results, which may impair speech, movement, memory or vision.
A number of benign and malignant tumors of the head and neck can be treated by INR. Embolization of the arterial supply of vascular tumor of the head and neck has become an accepted preoperative adjunct. Intracranial intra-arterial chemotherapy may be useful for the treatment of metastases or primary tumors of the brain.